File:Serpin mechanism.png
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Qoraal kooban
| Sharaxaad |
English: Serine proteases operate by a two-step catalytic mechanism. First, the substrate (blue) is attacked by the catalytic triad (red) to form an acyl-enzyme intermediate. The intermediate is typically resolved by hydrolysis by water. However, when the reactive centre loop (RCL) of a serpin is attacked, the conformational change (blue arrow) pulls the catalytic triad out of position, preventing it from completing catalysis. (Based on PDB: 1K9O, 1EZX) |
| Taariikhda | |
| Xigasho | Shaqadayda |
| Qoraa | Thomas Shafee |
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I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution 4.0 International license.
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| Taariikhda/Waqtiga | Sawir yar | Cabirka | Isticmaale | Ka hadalka | |
|---|---|---|---|---|---|
| kan hadda | 09:56, 22 Diseembar 2015 | | 1,800 × 1,488 (513 KB) | Evolution and evolvability | Higher resolution |
| 05:19, 19 Diseembar 2015 |  | 1,362 × 1,126 (300 KB) | Evolution and evolvability | Minor arrow correction | |
| 05:08, 19 Diseembar 2015 |  | 1,362 × 1,126 (300 KB) | Evolution and evolvability | added arrow and removed transparency | |
| 05:04, 19 Diseembar 2015 |  | 1,362 × 1,114 (360 KB) | Evolution and evolvability | Cross-wiki upload from en.wikipedia.org |
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