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English: Computer-generated Model of Purine Nucleoside Phosphorylase (PNP)
Purine Nucleoside Phosphorylase (PNP) is an important target enzyme for the design of anti-cancer and immunosuppressive drugs. Bacterial PNP, which is slightly different from the human enzyme, is used to synthesize chemotherapeutic agents. Knowledge of the three-dimensional structure of the bacterial PNP molecule is useful in efforts to engineer different types of PNP enzymes, that can be used to produce new chemotherapeutic agents. This picture shows a computer model of bacterial PNP, which looks a lot like a display of colorful ribbons. Principal Investigator was Charles Bugg.
Français : Modèle informatique de la Purine Nucléoside Phosphorylase (PNP)
La PNP est e nouveaux agents chémothérapeutiques. Cette image a été réalisée par une équipe dirigée par Charles Bugg.
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Science Directorate at Marshall Space Flight Center (MSFC) (NASA), MSFC Negative Number: 8772406, Reference Number: P-2757

9ssion from NASA.
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This image or video was catalogued by one of the centers of the United States National Aeronautics and Space Administration (NASA) under Photo ID: MSFC-8772406.

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PNP enzyme model

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